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Responsable del servicio
Mª Jesús Serrano Andrés

Faculty of Veterinary Medicine

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Spray drying, encapsulation and particle sizing

Spray drying of food and other products, microencapsulation of products and particle size measurement by laser diffraction.

  1. Spray drying/nanoencapsulation
  2. Microencapsulation
  3. Particle size measurement by laser diffraction in dry method
  4. Particle size measurement by laser diffraction in liquid process

Feature 1 aims to remove the aqueous content of products by a rapid drying technique, which minimally damages the compounds of interest, so it can be used in the processing of a wide range of products, including food. In addition, it can be used to microencapsulate certain products while preserving their properties (functional compounds, fermenting microbiota, proteins, etc.), resulting in dry encapsulations of 2-25 µm. Examples: drying of milk, corn starch, dyes, etc. and encapsulation of probiotics, functional compounds and others.

Feature 2 allows to generate beads and encapsulate liquids resulting in spheres in the size of 150 µm - 4 mm, functionality widely used in the food industry, pharmaceutical, nutraceutical industry, etc. Applications:

  • Encapsulation of oils
  • Encapsulation of probiotics
  • Helicobacter pylori treatment
  • Increased survival at intestinal level
  • Encapsulation of polymers
  • Capsules for cosmetics
  • Conservation of animal spermatozoa
  • Cell therapy (e.g. stem cells in osteoarthritis treatment).

The features 3 and 4 complete the two previous ones, since they allow the exact measurement of particle size, both of those suspended in liquid media and of dry particles. In addition, it can be directly useful for other research groups that, without using features 1 and 2, may require the measurement of the particle size of a given product and even the cell size of eukaryotic and many prokaryotic cells in the course of their research.


  • Dry measurement: for powdery materials with particle size between 0.1 -1000 µm.
  • Liquid measurement: for dispersions and emulsions with particle sizes between 0.1 - 200 µm.
  1. Mini Spray Dryer BÜCHI B-290
  2. Encapsulador BÜCHI B-395PRO
  3. Mastersizer 3000E Malvern Panalyical

Modalities of service features:

Services 1 and 2 can be carried out by Institute personnel, although self-service is also available (only available for internal requests and personnel who have received the necessary training). There are plans to include a new service that includes basic training in the use of the equipment in self-service mode, aimed at internal personnel who wish to use it in self-service mode.

In the case of the self-service mode, the user will be responsible for carrying out the analyses, always under the supervision of a member of the SCT. Self-service does not include consumables, which must be purchased by the user.